June 2023:

We further showed two case studies of genes STAT1 and IRF7, that AG-gain variants inside the high-risk region led to misspliced products, whilst the ones outside the region did not.

Feb 2023:

AGAIN webserver & GitHub was launched.

Dec 2022:

A germline homozygous intronic AG-gain variant was detected in the known anti-mycobacterial gene SPPL2A in a patient with mycobacterial disease, and experimentally validated.

Sep 2022:

AGAIN prototype was completed.

Jan 2022:

Inspired by BPHunter study, AGAIN idea was conceived.