Only variants in more than 1 individual (not singleton, AC > 1)
Only variants existing homozygous alleles (HOM >= 1)
Please provide the first 5 columns (CHROM, POS, ID, REF, ALT) of the varaints in VCF format. If no ID, fill it by a dot. It's required to provide the computed CADD scores in the 6th column. Please be consistent with the genome and CADD versions.